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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCB1
All Species:
15.15
Human Site:
T1030
Identified Species:
27.78
UniProt:
P08183
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08183
NP_000918.2
1280
141479
T1030
T
E
G
L
M
P
N
T
L
E
G
N
V
T
F
Chimpanzee
Pan troglodytes
XP_519183
1280
141455
T1030
T
E
G
L
T
P
N
T
L
E
G
N
V
T
F
Rhesus Macaque
Macaca mulatta
NP_001028059
1283
141504
T1033
T
E
G
L
K
P
N
T
L
E
G
N
V
T
F
Dog
Lupus familis
XP_539461
1269
140189
T1022
Q
E
G
K
K
T
D
T
C
E
G
N
I
E
F
Cat
Felis silvestris
Mouse
Mus musculus
P21447
1276
140628
M1026
T
Q
G
L
K
P
N
M
L
E
G
N
V
Q
F
Rat
Rattus norvegicus
P43245
1277
141369
W1030
T
E
G
L
K
P
N
W
L
E
G
N
V
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508941
1368
147746
S1118
D
R
G
L
K
P
V
S
S
P
G
A
P
G
A
Chicken
Gallus gallus
XP_418636
1307
144961
M1057
E
E
G
E
K
P
K
M
F
G
G
N
I
T
F
Frog
Xenopus laevis
NP_001081394
1287
141487
N1039
D
Q
G
E
K
P
K
N
C
S
G
N
V
V
F
Zebra Danio
Brachydanio rerio
XP_001922717
1340
147081
T1092
E
S
G
E
R
P
S
T
F
S
G
N
I
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00748
1302
143766
A1050
G
T
I
K
N
T
L
A
K
Q
L
N
L
F
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34712
1321
145045
K1071
L
S
L
A
G
E
K
K
K
L
Y
G
K
V
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80725
1286
139009
N1037
E
S
G
R
V
L
D
N
V
K
G
D
I
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96
55.7
N.A.
87.1
80.6
N.A.
62.1
69.6
67.6
56
N.A.
41.1
N.A.
44.5
N.A.
Protein Similarity:
100
99.8
97.7
75.4
N.A.
93.3
90.1
N.A.
76.6
83.6
81.8
73.5
N.A.
60.4
N.A.
62.6
N.A.
P-Site Identity:
100
93.3
93.3
46.6
N.A.
73.3
80
N.A.
26.6
46.6
40
40
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
93.3
93.3
60
N.A.
80
80
N.A.
33.3
53.3
46.6
53.3
N.A.
20
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
0
16
0
0
0
0
8
0
8
0
% D
% Glu:
24
47
0
24
0
8
0
0
0
47
0
0
0
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
16
0
0
0
0
8
70
% F
% Gly:
8
0
85
0
8
0
0
0
0
8
85
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
31
0
8
% I
% Lys:
0
0
0
16
54
0
24
8
16
8
0
0
8
8
0
% K
% Leu:
8
0
8
47
0
8
8
0
39
8
8
0
8
0
8
% L
% Met:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
39
16
0
0
0
77
0
0
0
% N
% Pro:
0
0
0
0
0
70
0
0
0
8
0
0
8
0
0
% P
% Gln:
8
16
0
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
24
0
0
0
0
8
8
8
16
0
0
0
0
0
% S
% Thr:
39
8
0
0
8
16
0
39
0
0
0
0
0
31
0
% T
% Val:
0
0
0
0
8
0
8
0
8
0
0
0
47
16
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _